Migraine

Hi Everyone,

I was just wondering something. While phenergan helps with nausea and often helps me sleep, which are 2 WONDERFUL things when dealing with a migraine, it also seems to stay in my body long after it has done it's job. If I use it on a Monday, I'm still groggy and foggy on Wednesday.

Has anyone else ever experienced this and, if so, what did you do?

Blessings,

Sandi

I've never had Phenergan.

But I have been groggy for a day or two after migraines quite frequently. I'd wonder if it wasn't just postdrome/migraine hangover more than any residual effects from the Phenergan if I was in your place.

Hi Sandi,

I always use phenergan for my nausea during migraine. I take it in 3 different forms--injection, pill, or suppository. I don't really get drowsy from the pill form--I can take as much as 50mg and still do my daily stuff without feeling wiped out.

When I use the injection or suppository, I do tend to feel a little more tired than with the pill. It sometimes helps me to sleep, but this effect wears off in a couple of hours.

I've never felt lingering sleepiness or fogginess from it...

(But remember, that's just me! You may want to ask your doc if he/she sees this effect with other patients.)

jenny

I usually take the suppositories, and they never make me tired or sleepy.

I've only used promethazine (generic for Phenergan) in tablet form. The first few times I took it, it would knock me out within about 15 minutes of taking it. Now it sometimes makes me a bit drowsy. The only other side effect I get from it sometimes is tremors, but not intolerably.

I do get a hungover, dragged out postdrome from my migraines sometimes though.

Drooly: I have experienced post drome symptoms before, but not of this magnitude. I believe it comes more from the drug, since I have used Phenergan when I was sick to my stomach from something NOT migraine related, and it knocked me for a loop.

Jenny: It's funny you mention that different forms can affect you in different ways. I've always used Phenergan in the pill form but my husband thought that maybe it was lingering in my system because of not digesting it quickly enough (He always has an idea about EVERYTHING) Hee Hee... he means well. Anyway, I quit taking the pill form and got the suppositories from my neuro. I thought maybe it would act differently. NOPE... same thing.

Valerie: I WISH it were the same for me. One thing is FOR SURE... our bodies are all SO different and can act totally opposite. I'm thinking that maybe this just isn't the right medication for me.

MJ: I've never gotten tremors from Phenergan. But now that I think about it, how would I really know? If I'm so out of it everytime I take it then maybe there is a LOT I don't realize.

Thanks, everyone.

~Sandi~

Hi Sandi,

I take a generic for phenergan very infrequently. But, when I do, it wipes me out for a whole 24 hours after I've taken it. I can start to function, but I feel like I'm in a haze and sleepy and just an overall fogginess.

Perhaps there is another med that you could try that wouldn't wipe you out so much. Zofran takes away my mild-moderate nausea but doesn't make me sleepy.

Kelly

Kelly,

Thank you SO much. It sounds like Phenergan does the same thing to you that it does to me. I "can" function, but it's very difficult. I've never heard of Zofran. I'll ask my neuro about it.

Blessings,

Sandi

Sandi,

I took zofran for nausea during pregnancy. I also get injections of it in my ER if I just can't keep anything down for LONG periods of time. For me, it hasn't been sedating at all. It's a medicine often used for cancer patients to help with the nausea that happens during chemotherapy...It works pretty well for my migraine nausea and vomiting.

Just a word of warning, though. It's pretty expensive (as far as nausea meds go, anyway). If you have good prescription coverage, though, that shouldn't be an issue...

jenny

Thanks for the "word of warning", Jenny. My prescription coverage is generally very good, so I hope it won't be a problem.

Sarah did have short term exhaustion with Phenegran but not so much of the long term like you.

We are now trying Reglin (sp?) I gave her one yesterday and it really knocked her out which was not good at school but today we just took half and that seemed to help. I wonder if you could do that with Phenegran but still get the needed relief?

Just an idea
Melanie
lovemykids411

I have tried both Zofran and Phenegren during my pregnancies for the severe morning sickness I had. Only the Zofran worked for me. (It was my life-saver.) And it does not make me sleepy. (Phenegren usually works for my nausea when I'm not pregnant, but didn't help the morning sickness.)

When I take phenegren it almost knocks me out and I could sleep for a day after I take it. I also have postdrome after a migraine and it's more of a foggy/yucky feeling whereas the after-phenegren feeling is more of a sleepy feeling (if that makes any sense).

Ursula

I have several things to take for nausea (migraine associated nausea), reglan, compazine and phenergan. The compazine helps the least, but if I'm only sightly nauseous, I'll take it because it doesn't make me sleepy.

Reglan makes me drowsy and I feel pretty hung over afterwards, and it really doesn't help any more than the compazine. I really don't care for it. For some reason my neuro is big on it.

phenergan works the best out of the three for my nausea. however... it is the worst when it comes to making me sleepy! I'm literally so drowsy I'll fall asleep in mid-conversation. Sleeping isn't a bad thing though if I have a bad migraine! It DOES seem to take a few days to really get out of my system. I think it's a combination of the phenergan PLUS postdrome. Put them together, and BAM, I'm a foggy befuddled mess for a few days!

I had IV Phenergan last Friday and found out that I completely cannot tolerate it in IV form. (Can't tolerate Reglan either.) The side effects it gave me were pretty awful - wooziness, dizziness, nausea, depressed breathing, extreme sedation, trouble speaking, mild hallucinations. The NP gave me some Zofran to counteract the increased nausea, which did help, and luckily all the other ones eventually wore off, but I was pretty miserable for a while.

Reglan seems mild in comparison now - it just makes me extremely anxious, woozy and dizzy. I think I'll be sticking with Zofran in IVs.

PHENERGAN knocks me down for 2 days when I get it through IV mixed with strong narcotics in the ER. I could sleep forever!!! My husband has to drag me out of bed!!!! I asked for something different and they gave me zofran. I had a much better time awakening!!! I am switching